I previously wrote a blog post about using pixi’s tasks feature to fix missing dependency issues with Bioconductor packages (like GenomeInfoDbData, BSgenome.Hsapiens.UCSC.hg38, etc.) after installation. At the time, I only knew the problem existed but didn’t understand the root cause — I was just providing a less-than-ideal workaround.

But recently, with insights from AI responses, I finally figured out the real reason — it all comes down to the post-link script mechanism in the Conda ecosystem.

I maintain a package channel on prefix.dev to distribute some self-built packages. Since I’ve been busy with work recently, I haven’t looked after it for a while. Today I checked and noticed that the Actions had mysteriously stopped running… So I looked into the reason and decided to document a few other issues as well.

New tools are always like this: the good parts are amazing, but the unfinished parts can be a headache. Recently, I tried to set up an automated build system using pixi and rattler‑build to regularly package and upload opencode to prefix.dev. The whole process took about 6 hours, during which I encountered quite a few unexpected issues.

Previously, I had tried modifying and adding recipes to conda channels. This time, I want to package my DevSSH and upload it to my own channel. I decided to try building a conda package myself.

In CI/CD workflows, dependency management is often a key factor determining build efficiency and reliability. Recently, I tried the setup-pixi GitHub Action in a static website deployment pipeline.

Recently, I attempted to use pixi to compile and run podman on FydeOS. While I made some progress, it ultimately only achieved half success. In this blog post, I’ll share the entire process and the issues encountered.

When using pixi to manage bioinformatics analysis environments, we often encounter issues where some Bioconductor R packages show missing dependencies after installation. The exact cause of this problem is currently unclear. After using pixi for a year, this issue still hasn’t been fixed (as of October 2025). This article introduces how to use pixi’s tasks feature to resolve such problems.

I’ve had the Fydetab Duo for over a month, and I’m still trying to find ways to make the most use of this device. At the very least, I’d like to write some blogs during my downtime with it. Hence the following exploration.

Bioinformatics is an interdisciplinary field, and the toolkit or technology stack used in bioinformatics is also quite “interdisciplinary”. The level of fragmentation is, in my opinion, absolutely not less than that of Linux distributions… This also brings us a common challenge: the deployment of bioinformatics analysis environments.